重症肌无力日常生活活动概况
Myasthenia gravis activities of daily living profile.
作者信息
Wolfe G I, Herbelin L, Nations S P, Foster B, Bryan W W, Barohn R J
机构信息
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75235-8897, USA.
出版信息
Neurology. 1999 Apr 22;52(7):1487-9. doi: 10.1212/wnl.52.7.1487.
The authors have developed an MG activities of daily living (ADL) profile (MG-ADL)-a simple eight-question survey of MG symptoms. In 254 consecutive encounters with established MG patients, the authors compared scores from the MG-ADL to the quantitative MG score (QMG)-a standardized, reliable scale used in clinical trials. The mean MG-ADL score was 4.89+/-3.63. The mean QMG score was 10.80+/-5.70. Pearson's correlation coefficient was 0.583 (p < 0.001). The MG-ADL is an easy-to-administer survey of MG that correlates well with the QMG and can serve as a secondary efficacy measurement in clinical trials.
作者们开发了一种重症肌无力日常生活活动（MG-ADL）量表——一项针对重症肌无力症状的简单的八问题调查问卷。在对254例确诊的重症肌无力患者的连续随访中，作者们将MG-ADL量表的得分与定量重症肌无力评分（QMG）进行了比较，QMG是一种在临床试验中使用的标准化、可靠的量表。MG-ADL量表的平均得分为4.89±3.63。QMG量表的平均得分为10.80±5.70。皮尔逊相关系数为0.583（p<0.001）。MG-ADL量表是一种易于实施的重症肌无力调查问卷，与QMG量表相关性良好，可作为临床试验中的次要疗效指标。
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