白塞病免疫抑制治疗后伴7号染色体单体的骨髓增生异常综合征
Myelodysplastic syndrome with monosomy 7 after immunosuppressive therapy in Behçet's disease.
作者信息
Bangerter M, Griesshammer M, v Tirpitz C, Krauter J, Heil G, Hafner M, Kern W, Heiss M, Kern P
机构信息
Department of Medicine III, University of Ulm, Germany.
出版信息
Scand J Rheumatol. 1999;28(2):117-9. doi: 10.1080/030097499442595.
Only few cases of Behçet's and hematological malignancies have been reported until now. We recently observed a 39-year-old female patient with Behçet's disease developing a myelodysplastic syndrome (MDS) FAB subtype refractory anemia with excess of blasts in transformation [RAEB-t] with a monosomy 7 after being treated with cyclosporin A and chlorambucil for several years. This case is reported and the occurrence of hematological malignancies and Behçet's disease is reviewed.
迄今为止，仅有少数白塞病与血液系统恶性肿瘤相关的病例报道。我们最近观察到一名39岁患有白塞病的女性患者，在用环孢素A和苯丁酸氮芥治疗数年之后，发展为骨髓增生异常综合征（MDS）FAB亚型——转化中的原始细胞过多的难治性贫血[RAEB-t]，伴有7号染色体单体。本文报道了该病例，并对白塞病与血液系统恶性肿瘤的发生情况进行了综述。
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