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一名骨髓增生异常综合征患者并发白塞病。

Behçet's disease in a patient with myelodysplastic syndrome.

作者信息

Kovacs Erzsebet, Nemeth Hajnalka, Telek Bela, Ujfalusi Aniko, Balogh Erzsebet, Pasztor Eva, Pfliegler Gyorgy

机构信息

Division of Rare Diseases, Second Department of Medicine, University of Debrecen Medical and Health Science Centre, Debrecen, Hungary.

出版信息

Clin Lymphoma Myeloma. 2009 Dec;9(6):459-61. doi: 10.3816/CLM.2009.n.090.

Abstract

A 75-year-old man presented with painful oral and groin ulcers. The lack of any infections and the location of the ulcers suggested Behçet's disease. Subsequently, pancytopenia developed and bone marrow examination revealed myelodysplastic syndrome. Cytogenetic examination revealed 7q- and 20q- but not 8+. Immunosuppressive therapy with cyclosporine and corticosteroid resulted in a dramatic improvement in both clinical signs and hematologic abnormalities.

摘要

一名75岁男性出现口腔和腹股沟疼痛性溃疡。无任何感染迹象且溃疡部位提示为白塞病。随后出现全血细胞减少,骨髓检查显示骨髓增生异常综合征。细胞遗传学检查发现有7号染色体长臂缺失(7q-)和20号染色体长臂缺失(20q-),但无8号染色体三体(8+)。使用环孢素和皮质类固醇进行免疫抑制治疗后,临床症状和血液学异常均有显著改善。

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