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[气球样变导致的二尖瓣关闭不全。70例手术病例系列研究]

[Mitral valve insufficiency due to ballooning. A surgical series of 70 cases].

作者信息

Baehrel B, Gandjbakhch I, Sahnoun Y, Cham B, Etievent P, Guiraudon G, Cabrol C

出版信息

Arch Mal Coeur Vaiss. 1978 Sep;71(9):982-90.

PMID:102299
Abstract

The authors report 70 cases of mitral regurgitation due to ballooning. For the surgeon this is the most frequent cause of degenerative mitral regurgitation in patients around 60-years-old. The aetiology still remains unknown. There are two opposing theories--the congenital and the acquired. The appearances at operation are characteristic--a localised or diffuse ballooning of one or both cusps with elongation of the chordae attached to the ballooned portion. Two histological features are noted--myxomatous degeneration of the cusp and the absence of any inflammatory process. Ballooning may be asymptomatic and bening for a long time before evolving progressively or suddenly into important mitral regurgitation. The pre-operative diagnosis is aided by left ventricular angiography and echocardiography. Surgical treatment, guided by the findings at operation, usually involves mitral valve replacement or, less frequently, mitral valve repair.

摘要

作者报告了70例因瓣叶膨出导致的二尖瓣反流病例。对于外科医生来说,这是60岁左右患者退行性二尖瓣反流最常见的原因。其病因仍然不明。有两种相反的理论——先天性和后天性。手术中的表现具有特征性——一个或两个瓣叶局部或弥漫性膨出,附着于膨出部分的腱索延长。有两个组织学特征——瓣叶黏液样变性和无任何炎症过程。瓣叶膨出可能在很长一段时间内无症状且为良性,然后逐渐或突然发展为严重的二尖瓣反流。术前诊断借助左心室血管造影和超声心动图。手术治疗根据术中发现进行指导,通常包括二尖瓣置换术,较少情况下为二尖瓣修复术。

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