Vajramani G, Devi I, Santosh V, Hegde T, Das B S, Das S, Shankar S K
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
Childs Nerv Syst. 1999 Mar;15(2-3):140-4. doi: 10.1007/s003810050353.
Benign triton tumor (neuromuscular hamartoma) is a rare tumor of the peripheral nerves, comprising mature neural and striated muscle elements. We report the third case, according to the literature, of a benign triton tumor affecting the Vth cranial nerve in a 4-year-old male child. The tumor was seen to involve the mandibular division of the trigeminal nerve in the infratemporal fossa and extend intracranially by eroding the base of middle cranial fossa. The mass was totally excised. In the tumor, bundles of axons intermingling with fascicles of relatively mature skeletal muscle were found. This type of hamartomatous lesions of neuroectodermal-mesenchymal origin could have arisen as the result of incorporation of mesenchymal tissue into nerve sheaths during embryogenesis or aberrant differentiation of neuroectodermal component into mesenchymal elements.
良性蝾螈瘤（神经肌肉错构瘤）是一种罕见的周围神经肿瘤，由成熟的神经和横纹肌成分组成。据文献报道，我们报告了第三例影响一名4岁男童第五颅神经的良性蝾螈瘤。肿瘤见于颞下窝的三叉神经下颌支，并通过侵蚀中颅窝底部向颅内扩展。肿块被完全切除。在肿瘤中，发现成束的轴突与相对成熟的骨骼肌束相互交织。这种神经外胚层-间充质起源的错构瘤性病变可能是由于胚胎发育过程中间充质组织并入神经鞘或神经外胚层成分异常分化为间充质成分所致。
