Langenscheidt P, Lang C, Püschel W, Feifel G
Department of General Surgery, University of Sarre, Homburg, Germany.
Eur J Surg. 1999 Mar;165(3):248-52. doi: 10.1080/110241599750007126.
In view of the high appendicectomy rate in a university teaching hospital in a developing country, we investigated the regional epidemiology of appendicitis.
Prospective clinical and pathological study.
Teaching hospital, Madagascar.
165 patients who underwent appendicectomy during a two month period.
Clinical investigation and histopathological examination of removed appendixes.
Appendicitis score, local incidence of appendicectomy, appendicitis, perforation, and negative appendicectomy.
There was a high incidence of primary appendicectomy (51.1/10,000 population/year) in relation to the incidence of histologically confirmed appendicitis (7.7/10,000), resulting in a negative appendicectomy rate of 85% (43/10,000). There were considerable sex related differences in the incidence of primary appendicectomy (81/10,000 women/year; 22/10,000 men), appendicectomy for appendicitis (12/10,000 women/year; 4/10,000 men) and non-perforating appendicitis (8/10,000 women/year; 2/10,000 men), but much less in that of perforating appendicitis (4/10,000 women/year; 2/10,000 men).
There is potential for more economic use of medical resources by reducing the rate of negative appendicectomy. The incidence of non-perforating appendicitis depends on the number of appendicectomies done, which may explain the differences observed in the incidence of appendicitis between industrialised and developing countries.
鉴于某发展中国家一所大学教学医院的阑尾切除率较高,我们对阑尾炎的地区流行病学进行了调查。
前瞻性临床与病理研究。
马达加斯加的教学医院。
在两个月期间接受阑尾切除术的165例患者。
对切除的阑尾进行临床调查和组织病理学检查。
阑尾炎评分、阑尾切除术的局部发生率、阑尾炎、穿孔及阴性阑尾切除术。
与组织学确诊的阑尾炎发病率(7.7/10000)相比,原发性阑尾切除术的发病率较高(51.1/10000人口/年),导致阴性阑尾切除率为85%(43/10000)。原发性阑尾切除术的发病率(81/10000女性/年;22/10000男性)、因阑尾炎进行的阑尾切除术的发病率(12/10000女性/年;4/10000男性)以及非穿孔性阑尾炎的发病率(8/10000女性/年;2/10000男性)存在显著的性别差异,但穿孔性阑尾炎的发病率差异较小(4/10000女性/年;2/10000男性)。
通过降低阴性阑尾切除率,有可能更经济地利用医疗资源。非穿孔性阑尾炎的发病率取决于阑尾切除术的数量,这可能解释了工业化国家和发展中国家阑尾炎发病率存在差异的原因。