Davies C, Schick B, Kronsbein H, Hendus J
Klinik für HNO-Krankheiten, Kopf-, Hals- und Plastische Gesichtschirurqie, Kommunikationsstörungen, Städtisches Klinikum Fulda.
HNO. 1999 Mar;47(3):183-7. doi: 10.1007/s001060050379.
Hemangiopericytomas are mesenchymal tumors and account for about 1% of all CNS tumors. Aggressive growth, tendency to local recurrence and relatively frequent metastases are the clinical features of these tumors. Histological characteristics are marked cellularity, vascularity and a dense net of reticular fibers. This case presents a patient with a local recurrence of a right temporal, atypical meningioma that had been operated on and irradiated elsewhere. After embolization large parts of the tumor were removed palliatively. Histological aspects of the resected tumor were consistent with a diagnosis of an atypical meningioma. Not until hepatic metastases from this tumor were found was the diagnosis re-examined and corrected to a malignant meningeal hemangiopericytoma. Surgical resection of primary tumor with frequent controls and, if needed, postoperative radiation therapy is the treatment of choice. Furthermore metastasizing atypical meningiomas should be examined critically to determine if a hemangiopericytoma is present.
血管外皮细胞瘤是间叶组织肿瘤，约占所有中枢神经系统肿瘤的1%。生长迅速、有局部复发倾向以及相对频繁的转移是这些肿瘤的临床特征。组织学特征为细胞密集、血管丰富以及有致密的网状纤维网。该病例报告了一名患者，其右颞叶非典型脑膜瘤曾在其他地方接受手术和放疗后出现局部复发。栓塞后，大部分肿瘤被姑息性切除。切除肿瘤的组织学表现符合非典型脑膜瘤的诊断。直到发现该肿瘤发生肝转移后，才重新检查诊断并将其修正为恶性脑膜血管外皮细胞瘤。首选的治疗方法是手术切除原发肿瘤并频繁进行复查，必要时进行术后放疗。此外，对于发生转移的非典型脑膜瘤，应仔细检查以确定是否存在血管外皮细胞瘤。
