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Effects of anti-NADPH-cytochrome c reductase and anti-cytochrome b5 antibodies on the hepatic and pulmonary microsomal metabolism and covalent binding of the pulmonary toxin 4-ipomeanol.

作者信息

Sasame H A, Gillette J R, Boyd M R

出版信息

Biochem Biophys Res Commun. 1978 Sep 29;84(2):389-95. doi: 10.1016/0006-291x(78)90182-1.

DOI:10.1016/0006-291x(78)90182-1
PMID:102322
Abstract
摘要

相似文献

1
Effects of anti-NADPH-cytochrome c reductase and anti-cytochrome b5 antibodies on the hepatic and pulmonary microsomal metabolism and covalent binding of the pulmonary toxin 4-ipomeanol.抗NADPH-细胞色素c还原酶抗体和抗细胞色素b5抗体对肺毒素4-异戊烯醇的肝脏和肺微粒体代谢及共价结合的影响。
Biochem Biophys Res Commun. 1978 Sep 29;84(2):389-95. doi: 10.1016/0006-291x(78)90182-1.
2
Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system.4-异戊二烯醇的代谢产物与兔肺和肝微粒体蛋白以及肺细胞色素P-450依赖性单加氧酶系统的酶的共价结合。
J Pharmacol Exp Ther. 1983 Jan;224(1):252-7.
3
In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes.大鼠肺和肝微粒体对肺毒素4-异戊二烯醇代谢激活的体外研究。
J Pharmacol Exp Ther. 1978 Dec;207(3):677-86.
4
Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
Biochem Biophys Res Commun. 1980 Apr 29;93(4):1167-72. doi: 10.1016/0006-291x(80)90612-9.
5
Evidence for molecular identity of microsomal and mitochondrial NADH-cytochrome b5 reductases of rat liver.大鼠肝脏微粒体和线粒体NADH-细胞色素b5还原酶分子同一性的证据。
J Biochem. 1978 Apr;83(4):1049-59. doi: 10.1093/oxfordjournals.jbchem.a131993.
6
Characteristics of a microsomal dechlorination system.微粒体脱氯系统的特性
Mol Pharmacol. 1975 Nov;11(6):809-17.
7
The in vitro formation of glutathione conjugates with the microsomally activated pulmonary bronchiolar aklylating agent and cytotoxin, 4-ipomeanol.谷胱甘肽与经微粒体激活的肺细支气管烷基化剂及细胞毒素4-异戊二烯醇在体外形成共轭物的过程。
J Pharmacol Exp Ther. 1980 Oct;215(1):97-103.
8
Immunohistochemical studies on electron transport proteins associated with cytochromes P-450 in steroidogenic tissues. II. Microsomal NADPH-cytochrome c reductase in the rat adrenal.类固醇生成组织中与细胞色素P-450相关的电子传递蛋白的免疫组织化学研究。II. 大鼠肾上腺中的微粒体NADPH-细胞色素c还原酶
Biochim Biophys Acta. 1979 Mar 7;583(2):148-58. doi: 10.1016/0304-4165(79)90422-7.
9
Subfractionation of rat liver microsomes by immunoprecipitation and immunoadsorption methods.通过免疫沉淀和免疫吸附方法对大鼠肝脏微粒体进行亚分级分离。
J Biochem. 1977 Mar;81(3):779-89. doi: 10.1093/oxfordjournals.jbchem.a131516.
10
The role of NADPH-cytochrome c reductase in microsomal hydroxylation reactions.NADPH-细胞色素c还原酶在微粒体羟化反应中的作用。
Arch Biochem Biophys. 1975 Sep;170(1):160-8. doi: 10.1016/0003-9861(75)90107-1.

引用本文的文献

1
Phase II study of 4-ipomeanol, a naturally occurring alkylating furan, in patients with advanced hepatocellular carcinoma.对晚期肝细胞癌患者进行的4-异戊烯醇（一种天然存在的烷基化呋喃）的II期研究。
Invest New Drugs. 2001;19(1):69-76. doi: 10.1023/a:1006408803734.
2
Ultrastructural pulmonary changes induced by intravenously administered 3-methylindole in goats.静脉注射3-甲基吲哚对山羊肺部造成的超微结构变化
Am J Pathol. 1980 Jun;99(3):551-60.