Chandra A K, Ray I, Ray P
Department of Life Sciences, Tripura University, Agartala.
Indian J Physiol Pharmacol. 1997 Jul;41(3):263-8.
To evaluate the iodine nutritional status, the thyroids of 3,577 school-age children of both sexes are examined clinically by palpation for goiter prevalence, 345 urine samples are analysed by dry ashing to determine the urinary iodine excretion pattern and 121 edible salt samples collected from house hold are analysed by iodometric titration to monitor the iodinatien achieved through salt from 6 representative areas of South Tripura in goiter endemic North East India. Endemic goiter is found prevalent in all the study areas though its occurrence varies from 13.95% to 30.96%, indicating that clinically mild to severe degree of iodine deficiency prevails in the region. But the pattern of median urinary iodine level of the studied population shows that there is no biochemical iodine deficiency. In 66.94% salt samples had iodine content less than the recommended level of 15 ppm. As per the classification recommended by WHO/UNICEF/ICCIDD, South Tripura falls into goiter endemic by clinical criteria and no endemicity by biochemical criteria. However, iodine deficiency disorders (IDD) continue to be prevalent in the region.
为评估碘营养状况,对3577名学龄儿童的甲状腺进行临床触诊检查,以确定甲状腺肿患病率;对345份尿液样本进行干灰化分析,以确定尿碘排泄模式;对从家庭收集的121份食用盐样本进行碘量滴定分析,以监测印度东北部甲状腺肿流行地区南特里普拉6个代表性地区通过食盐实现的碘化情况。尽管所有研究地区均发现地方性甲状腺肿流行,但其发生率在13.95%至30.96%之间有所不同,这表明该地区临床上存在轻度至重度碘缺乏情况。但研究人群的尿碘中位数水平模式表明不存在生化性碘缺乏。66.94%的盐样本碘含量低于15 ppm的推荐水平。根据世界卫生组织/联合国儿童基金会/国际控制碘缺乏病理事会推荐的分类标准,南特里普拉按临床标准属于甲状腺肿流行地区,按生化标准则无地方性流行情况。然而,碘缺乏病(IDD)在该地区仍然普遍存在。