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特里普拉邦地方性甲状腺肿病因中碘和硫氰酸盐的膳食供应情况

Dietary supplies of iodine and thiocyanate in the etiology of endemic goiter in Tripura.

作者信息

Chandra A K, Ray I

机构信息

Department of Physiology, University of Calcutta, University College of Science & Technology, 92, Acharya Prafulla Chandra Road, Kolkata-700 009.

出版信息

Indian J Pediatr. 2001 May;68(5):399-404. doi: 10.1007/BF02723011.

DOI:10.1007/BF02723011
PMID:11407152
Abstract

In the post-salt iodization phase, a study on iodine nutriture status was conducted in Tripura of North East India. The clinical variable of the study was goiter and the biochemical variables were urinary iodine and thiocyanate. Random sampling methodology was followed for selecting the study areas in the State. In each study area, the studied population consisted of school children of both sexes in the age group 6-15 years. The total study areas were 22 and the total number of the population was 10,801. The total number of urine samples were analysed for iodine and thiocyanate were 1,032 (about 10%). The total goiter rate was 21.63%. Population of most of the studied areas had no biochemical iodine deficiency as evidenced by median urinary iodine excretion levels. However, the per capita consumption of iodine of about 40% population was inadequate. A large number of cyanogenic plants (SCN precursors) are used as common vegetables. This study ensures that the existing goiter prevalence in the region could possibly due to non-uniform adequate iodine supply along with the thiocyanate load.

摘要

在食盐加碘阶段之后,对印度东北部特里普拉邦的碘营养状况进行了一项研究。该研究的临床变量是甲状腺肿,生化变量是尿碘和硫氰酸盐。采用随机抽样方法在该邦选择研究区域。在每个研究区域,研究人群包括6至15岁的男女学童。研究区域总数为22个,总人口为10801人。分析碘和硫氰酸盐的尿样总数为1032份(约10%)。甲状腺肿总患病率为21.63%。根据尿碘排泄中位数水平证明,大多数研究区域的人群没有生化碘缺乏。然而,约40%人口的人均碘摄入量不足。大量含氰植物(硫氰酸盐前体)被用作常见蔬菜。这项研究表明,该地区现有的甲状腺肿患病率可能是由于碘供应不足以及硫氰酸盐负荷不均匀所致。

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