Nordin P
Department of Dermatology, Lundby Hospital, 417 17 Gothenburg, Sweden.
Br J Dermatol. 1999 Feb;140(2):291-3. doi: 10.1046/j.1365-2133.1999.02665.x.
In this 5-year follow-up study, 60 auricular non-melanoma skin cancers, selected at a skin tumour clinic, were treated by a thorough curettage with different sized curettes followed by cryosurgery in a double freeze-thaw cycle. Tumours of the external auditory canal were excluded. Forty-seven basal cell carcinomas (BCCs), nine squamous cell carcinomas (SCCs), three Bowen's disease and one basisquamous cancer were included. The mean diameter of the malignancies was 18 mm (range 5-70). Morphoeiform BCCs, recurrent BCCs with fibrotic component and most of the SCCs were selected for Mohs' micrographic surgery. Forty-two patients with 47 tumours were followed-up for at least 5 years with only one recurrence. Thirteen patients, followed-up for 2-4 years, died from other causes with no sign of recurrence at their last visit. No major problems after treatment were registered and the cosmetic result was good or acceptable in all patients.
在这项为期5年的随访研究中,从一家皮肤肿瘤诊所挑选出60例耳部非黑色素瘤皮肤癌患者,先用不同尺寸的刮匙进行彻底刮除,然后进行双冻融循环的冷冻手术治疗。外耳道肿瘤被排除在外。其中包括47例基底细胞癌(BCC)、9例鳞状细胞癌(SCC)、3例鲍温病和1例基底鳞状细胞癌。恶性肿瘤的平均直径为18毫米(范围5 - 70毫米)。选择浸润性基底细胞癌、具有纤维化成分的复发性基底细胞癌以及大多数鳞状细胞癌进行莫氏显微外科手术。42例患有47个肿瘤的患者接受了至少5年的随访,仅有1例复发。13例患者随访2 - 4年,因其他原因死亡,最后一次就诊时无复发迹象。治疗后未出现重大问题,所有患者的美容效果良好或可接受。