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100例连续性耳廓非黑色素瘤皮肤癌刮除术联合冷冻手术的五年疗效

Five-year results of curettage-cryosurgery for 100 consecutive auricular non-melanoma skin cancers.

作者信息

Nordin Peter, Stenquist Bo

机构信息

Departments of Dermatology, Frölunda Specialist Hospital and Lundby Hospital, Gothenburg, Sweden.

出版信息

J Laryngol Otol. 2002 Nov;116(11):893-8. doi: 10.1258/00222150260369390.

DOI:10.1258/00222150260369390
PMID:12487665
Abstract

Large excisions or Mohs' micrographic surgery (MMS) are often the suggested treatments for non-melanoma skin cancers (NMSCs) of the external ear. This five-year follow-up attempts to evaluate whether curettage-cryosurgery could be an alternative therapy for selected auricular NMSCs. One hundred auricular NMSCs, selected at a skin tumour clinic, were treated by a thorough curettage, with different-sized curettes, followed by cryosurgery in a double freeze-thaw cycle. Seventy-seven basal cell carcinomas (BCCs), 13 squamous cell carcinomas (SCCs), six SCCs in situ, and four basosquamous carcinomas were included. The mean diameter of the tumours was 18 mm (range 5-70). Morphoeiform BCCs, recurrent BCCs with fibrotic component, and most of the SCCs were selected for MMS. Seventy-one patients with 81 tumours were followed-up for at least five years with only one recurrence. Nineteen patients with 19 tumours, followed-up for two to four years, died from other causes with no sign of recurrence at their last visit. Patients followed-up for less than two years were excluded. No major problems were registered after treatment. The cosmetic result was good or acceptable in most patients. In carefully selected patients a thorough curettage followed by freezing with liquid nitrogen in a double freeze-thaw cycle could be a safe and inexpensive therapy even for large NMSCs of the external ear.

摘要

对于外耳非黑色素瘤皮肤癌(NMSC),通常建议进行大面积切除或莫氏显微外科手术(MMS)。这项为期五年的随访旨在评估刮除术 - 冷冻手术是否可作为部分耳廓NMSC的替代疗法。在一家皮肤肿瘤诊所挑选了100例耳廓NMSC患者,先用不同尺寸的刮匙进行彻底刮除,然后进行双冻融循环的冷冻手术。其中包括77例基底细胞癌(BCC)、13例鳞状细胞癌(SCC)、6例原位SCC和4例基底鳞状细胞癌。肿瘤的平均直径为18毫米(范围5 - 70毫米)。浸润性BCC、伴有纤维化成分的复发性BCC以及大多数SCC被选作MMS治疗对象。71例患有81个肿瘤的患者接受了至少五年的随访,仅有1例复发。19例患有19个肿瘤的患者接受了两到四年的随访,死于其他原因,最后一次就诊时无复发迹象。随访时间不足两年的患者被排除。治疗后未记录到重大问题。大多数患者的美容效果良好或可接受。对于精心挑选的患者,即使是外耳较大的NMSC,彻底刮除后进行双冻融循环的液氮冷冻也可能是一种安全且廉价的治疗方法。

相似文献

1
Five-year results of curettage-cryosurgery for 100 consecutive auricular non-melanoma skin cancers.100例连续性耳廓非黑色素瘤皮肤癌刮除术联合冷冻手术的五年疗效
J Laryngol Otol. 2002 Nov;116(11):893-8. doi: 10.1258/00222150260369390.
2
Five-year results of curettage-cryosurgery of selected large primary basal cell carcinomas on the nose: an alternative treatment in a geographical area underserved by Mohs' surgery.鼻部特定大型原发性基底细胞癌刮除-冷冻手术的五年结果:在莫氏手术服务不足的地理区域的一种替代治疗方法
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Curettage-cryosurgery for non-melanoma skin cancer of the external ear: excellent 5-year results.外耳道非黑色素瘤皮肤癌的刮除术-冷冻手术:5年效果极佳
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Prospective follow-up after curettage-cryosurgery for scalp and face skin cancers.头皮和面部皮肤癌刮除-冷冻手术后的前瞻性随访。
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[Curettage and cryosurgery as a safe method for treatment of non-melanoma skin cancer of the nose and ear].刮除术及冷冻手术作为治疗鼻和耳部非黑色素瘤皮肤癌的一种安全方法
Lakartidningen. 1991 Jul 24;88(30-31):2523-5.
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[Curettage and cryosurgery of epithelial skin cancer. Good 5-year results in the treatment of nose and ear cancer].[上皮性皮肤癌的刮除术和冷冻手术。治疗鼻癌和耳癌的5年良好疗效]
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Cryosurgery in the treatment of basal cell carcinoma. Assessment of one and two freeze-thaw cycle schedules.冷冻手术治疗基底细胞癌。单冻融循环和双冻融循环方案的评估。
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The occurrence of residual or recurrent squamous cell carcinomas in organ transplant recipients after curettage and electrodesiccation.刮除术和电干燥术后器官移植受者中残余或复发性鳞状细胞癌的发生情况
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