Mueller UK, Wells M, Radevski I, Ouwerkerk J, Tager R, Sliwa K, Sareli P
Division of Cardiology, Baragwanath Hospital, University of the Witwatersrand, Johannesburg, South Africa.
Blood Press Monit. 1997 Dec;2(1):21-25.
To examine the extent to which one session of repeated automated (30-45 min) blood pressure measurements in non-treated, hypertensive patients can be used to predict daytime ambulatory blood pressure (ABP). METHODS: Two hundred untreated black hypertensive patients (mean age 50.2+/-11.2) were retrospectively stratified on the basis of the daytime ambulatory diastolic blood pressure (DBP) into mild, moderate and severe hypertensives (90 mmHg <DBP < 140 mmHg). Office blood pressure was determined at 3 min intervals for a total of 30-45 min using the Dinamap Critikon 1846 SX monitor. Twenty-four hour ambulatory blood pressure (ABP) was performed on the same day in all patients using a SpaceLabs 90207 device. RESULTS: The mean diastolic Dinamap measurements compared with the mean ambulatory daytime DBP were very similar in terms of 'traditional' statistics (mean: 114 +/- 14.6 versus 113 +/- 12 mmHg, correlation: 0.80). However, agreement analysis according to Bland and Altman showed a poor agtreement with an error as high as 19 mmHg. The mean systolic Dinamap measurements compared with the mean ambulatory daytime SBP were significantly overestimated (mean: 185 +/- 25.0 versus 170 +/- 19.3 mmHg, correlation 0.82) and the error was as high as 43 mmHg. On residual analysis, 75% of the diastolic Dinamap values and only 35% of the systolic Dinamap measurements were within an error of +/- 10 mmHg. The average of the first five Dinamap measurements had the greatest predictive ability for the daytime ABP. CONCLUSION: As a result of the poor agreement between the two methods, we suggest that, from the clinical point of view, the two techniques should be treated as two separate entities.
探讨在未经治疗的高血压患者中,进行一次重复自动(30 - 45分钟)血压测量在多大程度上可用于预测日间动态血压(ABP)。方法:200例未经治疗的黑人高血压患者(平均年龄50.2±11.2岁)根据日间动态舒张压(DBP)回顾性分层为轻度、中度和重度高血压患者(90 mmHg < DBP < 140 mmHg)。使用Dinamap Critikon 1846 SX监护仪每隔3分钟测定一次诊室血压,共测量30 - 45分钟。所有患者于同日使用SpaceLabs 90207设备进行24小时动态血压(ABP)监测。结果:就“传统”统计数据而言,Dinamap测量的平均舒张压与动态日间平均DBP非常相似(均值:114±14.6对113±12 mmHg,相关性:0.80)。然而,根据Bland和Altman法进行的一致性分析显示一致性较差,误差高达19 mmHg。Dinamap测量的平均收缩压与动态日间平均SBP相比显著高估(均值:185±25.0对170±19.3 mmHg,相关性0.82),误差高达43 mmHg。经残差分析,75%的Dinamap舒张压值和仅35%的Dinamap收缩压测量值误差在±10 mmHg以内。Dinamap前五次测量的平均值对日间ABP的预测能力最强。结论:由于两种方法之间一致性较差,我们建议,从临床角度来看,这两种技术应被视为两个独立的实体。