Lundin D V, Eros P A, Melloh J, Sands J E
Drug Intell Clin Pharm. 1980 May;14(5):335-42. doi: 10.1177/106002808001400503.
A pilot study to test the effectiveness of medication instruction was carried out using 61 voluntary participants age 65 and older. They were interviewed regarding their medication taking, and instruction was individualized using one of four teaching modes: oral; written; oral and written; and oral and written combined with memory aids. Postinstruction interviews revealed no significant difference in compliance among all groups. The preinstruction mean compliance score of all subjects was 98.8 percent. Although compliance, judged specifically on the basis of the prescription label instructions, was extremely high both before and after instruction, drug-taking behavior and knowledge did change. The preinstruction compliance score does not necessarily reflect safe or desirable drug-taking behavior. There was no specific information given to clients with their prescriptions and prescription medications, indicating, for drug-therapy decision makers, a much broader problem than non-compliance.
一项测试药物指导有效性的试点研究以61名65岁及以上的自愿参与者为对象展开。研究人员就他们的用药情况进行了访谈，并采用四种教学模式之一进行个性化指导：口头指导；书面指导；口头和书面指导；口头和书面指导并结合记忆辅助工具。指导后的访谈显示，所有组别的依从性没有显著差异。所有受试者指导前的平均依从性得分是98.8%。尽管根据处方标签说明具体判断的依从性在指导前后都极高，但用药行为和知识确实发生了变化。指导前的依从性得分不一定反映安全或理想的用药行为。在给客户开具处方和提供处方药时，没有提供具体信息，这表明对于药物治疗决策者来说，问题远比不依从更广泛。
