Radzivil G G, Mikheeva E V
Kardiologiia. 1976 Apr;16(4):106-12.
The total content of calcium and protein was studied in 50 patients during the initial 5 days after surgery for their congenital or acquired heart diseases conducted under extracorporeal circulation; in half of them the content of the dialysing fraction of total calcium and plasma albumins were also examined. The study has demonstrated that during the 1st postoperative day the content of the total and dialysing calcium is elevated which is due to the administration of calcium for the neutralization of citrate during blood transfusions. The greatest fluctuations of these values (both decreases and increases) were observed when the heart-lung machine was primed with blood containing 18.2--23mEg Ca++ per 1 1 of citrate blood. Within the early 5 postoperative days no restoration of the impaired calcium balance is observed in these patients, while the blood content of calcium is returning to the preoperative level. The blood content of calcium was studied after repeated injections of various doses of calcium. The most rational method proved to consist in repeated injections of 5ml of 10% CaCl2 solution every 30 min--1 hour which resulted in a moderate elevation of the blood content of the total and dialysing calcium.
对50例在体外循环下进行先天性或后天性心脏病手术的患者术后最初5天的钙和蛋白质总含量进行了研究；其中一半患者还检测了总钙的透析部分含量和血浆白蛋白含量。研究表明，术后第1天总钙和透析钙含量升高，这是由于输血期间为中和柠檬酸盐而补钙所致。当心肺机用每1升柠檬酸盐血中含18.2 - 23mEq Ca++的血液预充时，观察到这些值（下降和上升）波动最大。在术后早期5天内，这些患者未观察到受损钙平衡的恢复，而血钙含量正在恢复到术前水平。在反复注射不同剂量的钙后对血钙含量进行了研究。最合理的方法证明是每30分钟至1小时反复注射5ml 10%氯化钙溶液，这导致总钙和透析钙的血钙含量适度升高。
