Vittoria A, Laghi Pasini F
Quad Sclavo Diagn. 1976 Jun;12(2):113-22.
PAH clearance utilizing the standard technique with blood and urine collection was determined in thirty patients affected by various primary or secondary renal diseases. Each of these patients, also had a "bolus" infusion of p-aminohyppurate. "Bolus clearance" was calculated from the disappearance slope of their blood concentration. The "bolus clearance" of PAH correlated well with the standard technique. However "Bolus PAH clearance" overestimated the standard technique. This overestimated (236 ml/min) was significant and defined by a regression factor. Reasons are briefly discussed.