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[豚鼠大肠隐窝细胞有丝分裂周期G1期的分裂]

[Splitting of phase G1 of the mitotic cycle of guinea pig large intestine crypt cells].

作者信息

Gushchin V A

出版信息

Tsitologiia. 1976 Dec;18(12):1455-63.

PMID:1025793
Abstract

Changes in shape of the second wave of the labeled mitoses curve previously observed by Rowinski and Sawicki (1972) for three crypt zones of three different parts of guinea-pig ascending colon are explained by the complicated branching structure of the G1-phase. This structure is assumed to be the same for different crypt zones and for different sections of the intestine. Changes in shape of the second wave of the labeled mitoses curve are explained by the changes in distribution of proliferating cell stream between the alternative directions at the points of branching of the G1-phase, depending on the crypt zone, the intestine section, the cell state, and on the state of intestine.

摘要

罗温斯基和索维基(1972年)之前观察到豚鼠升结肠三个不同部位的三个隐窝区标记有丝分裂曲线第二波的形状变化,这是由G1期复杂的分支结构所解释的。假定这种结构对于不同的隐窝区以及肠道的不同节段是相同的。标记有丝分裂曲线第二波的形状变化是由G1期分支点处增殖细胞流在交替方向之间的分布变化所解释的,这种变化取决于隐窝区、肠道节段、细胞状态以及肠道状态。

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