Meerson F Z, Radzievskiĭ S A
Biull Eksp Biol Med. 1976 Aug;82(8):902-3.
Newborn male and female Wistar rats were adapted to hypoxia in a pressure chamber. Adaptation was started from the "altitude" of 1000 m, 1 hour daily, and then the time and the intensity of hypoxic actions were gradually increased: beginning from the 17th day the animals were subjected to adaptation to the "altitude" of 5000 m, for 5 hours, 5 days a week. The defence conditioned reflex of active avoidance was provoked in the animals after 2-month adaptation. A tendency to a more rapid elaboration of the reflex and a markedly enhanced degree of its retention in comparison with control was revealed in the adapted males. No significant changes in the elaboration and rentention of the reflex were found in the female animals adapted to hypoxia under analogous conditions.
新生的雄性和雌性Wistar大鼠在压力舱中进行低氧适应。适应从海拔1000米开始，每天1小时，然后逐渐增加低氧作用的时间和强度：从第17天开始，动物接受海拔5000米的适应，每周5天，每天5小时。在2个月的适应后，在动物身上诱发主动回避的防御性条件反射。与对照组相比，适应的雄性大鼠表现出反射形成更快的趋势以及反射保持程度明显增强。在类似条件下适应低氧的雌性动物中，未发现反射形成和保持有显著变化。
