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[耗氧量作为动物对高原低氧适应的指标]

[Oxygen consumption as an indicator of the adaptation of animals to altitude hypoxia].

作者信息

Malkin V B, Loginova E V

出版信息

Kosm Biol Aviakosm Med. 1984 Sep-Oct;18(5):47-50.

PMID:6513472
Abstract

Altitude chamber experiments have shown that the quantity of oxygen consumption in the posthypoxic period as an index of adaptation to hypoxia is of a low informative value: during the normal course of adaptation, oxygen consumption changes insignificantly or decreases slightly; it increases somewhat if the hypoxic atmosphere contains CO2 (pCO2 = 19 - 27 mm Hg) and declines significantly (by 22.6%) only if adaptation is disordered. At the same time oxygen consumption can be a highly informative index, characterizing the efficiency of adaptation to hypoxia only if it is measured immediately after exposure to acute hypoxia. In this experimental design the magnitude of oxygen consumption increases with increasing oxygen debt which, as follows from our experiments, shows the degree of conditioning to altitude hypoxia.

摘要

高空舱实验表明,作为缺氧适应指标的低氧后时期耗氧量信息价值较低:在正常适应过程中,耗氧量变化不显著或略有下降;如果低氧环境中含有二氧化碳(pCO2 = 19 - 27 mmHg),耗氧量会有所增加,只有在适应紊乱时才会显著下降(22.6%)。同时,耗氧量可以是一个信息丰富的指标,只有在急性缺氧暴露后立即测量时,才能表征缺氧适应的效率。在这种实验设计中,耗氧量随氧债增加而增加,正如我们的实验所示,这表明了对高原缺氧的适应程度。

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