Shorokhova V B
Biull Eksp Biol Med. 1976 Aug;82(8):952-3.
The influence of exogenous DNA on the content of endogenous DNA and the rate of biosynthesis was studied in rat bone marrow. After the injection of highly-polymerized homologous DNA to intact rats the content of rat DNA per 1 gm of the bone marrow decreased within the first 3 days (the most marked fall occurred in 3 days--by 36%), and returned to the normal by the 6th day. The rate of DNA biosynthesis in rat bone marrow increased in 18 hours (doublled in comparison with control), remained elevated within 6 days (by 58%) and approached the normal level from 1 to 3 days after the DNA injection.
在外源DNA对大鼠骨髓中内源性DNA含量和生物合成速率的影响的研究中，向健康大鼠注射高度聚合的同源DNA后，每克骨髓中大鼠DNA的含量在最初3天内下降（最明显的下降发生在第3天——下降了36%），并在第6天恢复正常。大鼠骨髓中DNA生物合成速率在18小时内增加（与对照组相比增加了一倍），在6天内保持升高（增加了58%），并在注射DNA后的1至3天接近正常水平。
