Jesudasan K, George B, Chacko C J, Taylor P M, Kurian P V, Job C K
Lepr India. 1976 Oct;48(4 Suppl):668-76.
This study using the dapsone/creatinine (D/C) ratio was undertaken to find out how many of the patients attending the Village Clinics were actually taking the DDS tablets. The Urine D/C ratio was estimated in 35 patients who were receiving a supervised daily dosage of either 50 or 100 mgs of DDS. The D/C ratio was also estimated in 100 out patients who were on either 50 or 100 mgs of dapsone. It was determined that 72% of this group had taken DDS in the previous 24 hours. It was also seen that the 55 patients who were receiving 100 mgs of DDS had taken 79.3% of their dapsone dosage, and the 45 patients receiving 50 mgs of DDS had taken 96% of their dosage.
本研究采用氨苯砜/肌酐（D/C）比值，以查明在乡村诊所就诊的患者中实际服用氨苯砜片的人数。对35名接受每日50毫克或100毫克氨苯砜监督剂量治疗的患者进行了尿D/C比值测定。还对100名服用50毫克或100毫克氨苯砜的门诊患者进行了D/C比值测定。结果确定，该组中有72%的患者在过去24小时内服用了氨苯砜。还发现，接受100毫克氨苯砜治疗的55名患者服用了其氨苯砜剂量的79.3%，而接受50毫克氨苯砜治疗的45名患者服用了其剂量的96%。
