Coltorti E A, Varela-Diaz V M
Ann Parasitol Hum Comp. 1976 Nov-Dec;51(6):647-52. doi: 10.1051/parasite/1976516647.
The release of antigens from hydatid cysts, essential for the induction of a detectable host antibody response, is considered to depend on alterations in the physical integrity of the cyst germinal membrane. This explanation, however, does not account for the detection of serologic responses in persons harbouring hyaline cysts unless it were possible for membrane microfissures to arise and provide an antigenic stimulus without adversely affecting cyst viability. The results of the present study have demonstrated that hydatid cysts are able to survive when experimentally punctured in vitro or in vivo. These findings on the capacity of hyaline cysts to repair or recuperate from a microfissure are consistent with the detection of antibody responses in persons harbouring hyaline hydatid cysts with apparently intact membranes and with the hypothesis of an association between integrity of cyst membranes and degree of host immunological responses.
棘球蚴囊肿释放抗原是诱导可检测到的宿主抗体反应所必需的，这一过程被认为依赖于囊肿生发膜物理完整性的改变。然而，这种解释无法说明在患有透明囊肿的人中检测到血清学反应的情况，除非有可能出现膜微裂缝并提供抗原刺激，同时又不会对囊肿的生存能力产生不利影响。本研究结果表明，棘球蚴囊肿在体外或体内被实验性穿刺后仍能存活。这些关于透明囊肿从微裂缝修复或恢复能力的发现，与在膜明显完整的透明棘球蚴囊肿患者中检测到抗体反应以及囊肿膜完整性与宿主免疫反应程度之间存在关联的假设相一致。
