Intramolecular determination of primary kinetic isotope effects in hydroxylations catalyzed by cytochrome P-450.
作者信息
Hjelmeland L M, Aronow L, Trudell J R
出版信息
Biochem Biophys Res Commun. 1976 May 23;76(2):541-9. doi: 10.1016/0006-291x(77)90758-6.
PMID:1027445
Abstract
摘要
相似文献
1
Intramolecular determination of primary kinetic isotope effects in hydroxylations catalyzed by cytochrome P-450.
Biochem Biophys Res Commun. 1976 May 23;76(2):541-9. doi: 10.1016/0006-291x(77)90758-6.
2
Intramolecular determination of substituent effects in hydroxylations catalyzed by cytochrome P-450.
Mol Pharmacol. 1977 Jul;13(4):634-9.
3
Prochiral selectivity and intramolecular isotope effects in the cytochrome P-450 catalyzed omega-hydroxylation of cumene.
Biochemistry. 1986 Nov 18;25(23):7336-43. doi: 10.1021/bi00371a015.
4
Intramolecular isotope effects associated with meta-hydroxylation of biphenyl catalyzed by cytochrome P-450.
Biochem Biophys Res Commun. 1984 Feb 14;118(3):867-72. doi: 10.1016/0006-291x(84)91475-x.
5
Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
FEBS J. 2006 May;273(10):2223-31. doi: 10.1111/j.1742-4658.2006.05235.x.
6
Cytochrome P450-catalyzed hydroxylation of hydrocarbons: kinetic deuterium isotope effects for the hydroxylation of an ultrafast radical clock.
Biochemistry. 1994 Sep 6;33(35):10630-7. doi: 10.1021/bi00201a009.
7
Intramolecular isotope effects for benzylic hydroxylation of isomeric xylenes and 4,4'-dimethylbiphenyl by cytochrome P450: relationship between distance of methyl groups and masking of the intrinsic isotope effect.
Biochemistry. 1997 Jun 10;36(23):7136-43. doi: 10.1021/bi962810m.
8
Cumene hydroperoxide-supported denitrification of 2-nitropropane in uninduced mouse liver microsomes.
Int J Biochem. 1986;18(7):595-601. doi: 10.1016/0020-711x(86)90239-9.
9
Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations.
J Am Chem Soc. 2003 May 21;125(20):6064-5. doi: 10.1021/ja0343858.
10
Evidence against an abstraction or direct insertion mechanism for cytochrome P-450 catalysed meta hydroxylations.
Biochem Biophys Res Commun. 1982 Jan 29;104(2):626-32. doi: 10.1016/0006-291x(82)90683-0.
引用本文的文献
1
Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions.
Methods Enzymol. 2017;596:217-238. doi: 10.1016/bs.mie.2017.06.036. Epub 2017 Jul 18.
2
Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps.
J Biol Chem. 2010 Mar 12;285(11):8031-44. doi: 10.1074/jbc.M109.088039. Epub 2010 Jan 8.
3
Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes.
Biochemistry. 2006 Jan 17;45(2):533-42. doi: 10.1021/bi051840z.
4
Intermolecular and intramolecular isotope effects in the deamination of putrescine catalyzed by diamine oxidase.
Experientia. 1982 Apr 15;38(4):431-3. doi: 10.1007/BF01952622.
Zotero 插件