猫牙髓内神经对牙本质化学和渗透压刺激的反应。

Responses of intradental nerves to chemical and osmotic stimulation of dentine in the cat.

作者信息

Horiuchi H, Matthews B

机构信息

Department of Physiology (Oral Biology), The Medical School, University Walk, Bristol BS8 1TD Great Britain.

出版信息

Pain. 1976 Mar;2(1):49-59. doi: 10.1016/0304-3959(76)90046-4.

DOI:10.1016/0304-3959(76)90046-4

PMID:1028019

Abstract

Recordings have been made of the neural responses evoked by stimulation of dentine with solutions of NaCl, NH4Cl and dextrose. Stimulation of the outer dentine produced no response. From the inner dentine, a smaller number of impulses were recorded with solutions of NaCl than with corresponding concentrations of NH4Cl, but a much larger number than with solutions of dextrose. The discharge evoked by a solution increased in mean frequency and decreased in latency as the thickness of dentine was reduced. The responses suggest that the receptors were in the innermost dentine or the pulp and that they were excited by changes in extracellular fluid composition rather than by osmotic effects. The properties of the receptors appear to be different from those involved in pain from dentine in man.

摘要

已记录了用氯化钠、氯化铵和葡萄糖溶液刺激牙本质所诱发的神经反应。刺激外层牙本质未产生反应。从内层牙本质记录到，与相应浓度的氯化铵溶液相比，氯化钠溶液诱发的冲动数量较少，但比葡萄糖溶液诱发的冲动数量多得多。随着牙本质厚度的减小，溶液诱发的放电平均频率增加，潜伏期缩短。这些反应表明，感受器位于最内层牙本质或牙髓中，它们是由细胞外液成分的变化而非渗透效应所激发。这些感受器的特性似乎与人类牙本质疼痛所涉及的感受器不同。