Lebedev A A, Kuz'min O B
Probl Endokrinol (Mosk). 1976 Jul-Aug;22(4):97-100.
A study was made of the influence of adrenaline of certain components of the transepithelial sodium transport system in the frog skin an on energy sources providing its activating effect. Adrenaline proved to increase the sodium transport through the frog skin decreasing its electrical resistance. Strophanthin K prevented the reaction of frog skin adrenaline completely. Monoiodacetate also produced an inhibitory action on the adrenaline effect which was eliminated on addition of pyruvate into the solution. Potassium cyanide and 2,4-dinitrophenol considerably weakened the adrenaline stimulation of transepithelial sodium transport. A conclusion was drawn that an increase of sodiun transport by the frog skin in the action of catecholamines was associated with increase of its ionic permeability and the activation of the ionic pump. It is supposed that the principal source of energy provision for the stimulating effect of catecholamines were processes of aerobic energy metabolism.
研究了肾上腺素对蛙皮跨上皮钠转运系统某些成分的影响以及为其激活作用提供能量的来源。结果证明，肾上腺素可增加蛙皮的钠转运并降低其电阻。毒毛花苷 K 可完全阻止蛙皮对肾上腺素的反应。碘乙酸盐也对肾上腺素的作用产生抑制作用，向溶液中加入丙酮酸后这种抑制作用消除。氰化钾和 2,4-二硝基苯酚大大减弱了肾上腺素对跨上皮钠转运的刺激作用。得出的结论是，儿茶酚胺作用下蛙皮钠转运的增加与其离子通透性的增加和离子泵的激活有关。据推测，儿茶酚胺刺激作用的主要能量供应来源是有氧能量代谢过程。
