地高辛和β-甲基地高辛的生物利用度。
Bioavailability of digoxin and beta-methyl-digoxin.
作者信息
Padeletti L, Fantini F, Cinelli P, Gremigni C
出版信息
J Int Med Res. 1976;4(5):352-4. doi: 10.1177/030006057600400509.
PMID:1028636
Abstract
In a randomized crossover study the bioavailability of a single dose of digoxin and of beta-methyl-digoxin tablets was tested in four normal volunteers. No difference was found between the two products in the rate and extent of drug absorption using 6 day cumulative urinary excretion and serial serum concentration measurements.
摘要
在一项随机交叉研究中，对4名正常志愿者测试了单剂量地高辛和β-甲基地高辛片剂的生物利用度。通过6天累积尿排泄量和系列血清浓度测定，发现两种产品在药物吸收速率和程度上没有差异。
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