Habibi B, Avril J, Fouillade M T, Lopez M, Vaucelle R, Salmon C
Haematologia (Budap). 1976;10(3-4):403-10.
A Caucasian French family was investigated including two Jk(a-b-) sibs who had developed anti-JkaJkb. The parents were first cousins. Quantitative study of Kidd antigens using titration scoring and HD50 assay clearly showed the parents and a maternal aunt, phenotypically Jk(a+b-), to have a weak expression of Jka documenting thereby the transmission of the postulated silent gene Jk. Absorption, elution and coagglutination assays revealed the cross reactivity of the antibody developed by the two sibs. Leucocytes and platelets from these two individuals were not shown to absorb anti-JkaJkb.
对一个法裔白种人家庭进行了调查,该家庭中有两名Jk(a-b-)同胞,他们产生了抗JkaJkb。父母是近亲。使用滴定评分和HD50测定法对基德抗原进行定量研究,清楚地表明父母以及一位表型为Jk(a+b-)的姨妈Jka表达较弱,从而证明了假定的沉默基因Jk的传递。吸收、洗脱和凝聚试验揭示了这两名同胞产生的抗体的交叉反应性。这两个人的白细胞和血小板未显示出能吸收抗JkaJkb。