Stratton C W
Hosp Formul. 1988 Aug;23(8):654-7.
Typically, P & T Committee antibiotic selection criteria have included such factors as cost, pharmacokinetics, side effects profile, spectrum of activity, and relative activity against specific pathogens. The microbiology laboratory can provide the P & T Committee with other useful information to help guide them in making even more appropriate and cost-effective formulary decisions. This information includes specific susceptibility data (including prevalence of pathogens, source of infection [community or nosocomial], anatomical site of isolates, specific unit or service where isolated, type of culture specimen, total number of pathogens in the hospital), resistance trends data, an evaluation of microbiologic data presented in published studies, further data regarding an antimicrobial's spectrum of activity and activity against specific pathogens, and the relevance and limitations of in vitro data. With this information in hand, P & T Committee should be in a much better position to optimize formulary decision-making.
通常，药品与治疗学委员会（P&T Committee）的抗生素选择标准包括成本、药代动力学、副作用情况、活性谱以及对特定病原体的相对活性等因素。微生物实验室可以为药品与治疗学委员会提供其他有用信息，以帮助指导他们做出更合适且具有成本效益的处方集决策。这些信息包括具体的药敏数据（包括病原体的流行情况、感染源[社区或医院获得性]、分离株的解剖部位、分离地点的具体科室或服务部门、培养标本类型、医院内病原体总数）、耐药趋势数据、对已发表研究中呈现的微生物学数据的评估、关于抗菌药物活性谱及对特定病原体活性的进一步数据，以及体外数据的相关性和局限性。掌握这些信息后，药品与治疗学委员会应能更好地优化处方集决策。
