Larrat E P, Mattea E J
Hosp Formul. 1986 Apr;21(4):497-9, 502-3.
Brompton's cocktail is an oral formulation used widely for intractable pain associated with cancer. In the United States, however, formulations are not standard, and questions concerning the efficacy and safety of some ingredients have been raised. Hospitals were surveyed to determine the formulation of Brompton's cocktail used, how the cocktail is compounded, and who is responsible for deciding on the pain cocktail formula. Controversy surrounding the use of cocaine as an ingredient is discussed, and problems with dating of formulations are described. P & T Committees are encouraged to review the literature concerning pain cocktail formulations and reevaluate the use of pain cocktails within their own institutions.
布朗普顿鸡尾酒是一种广泛用于治疗癌症相关顽固性疼痛的口服制剂。然而，在美国，其配方并不标准，一些成分的疗效和安全性也受到了质疑。我们对医院进行了调查，以确定所使用的布朗普顿鸡尾酒配方、该鸡尾酒的配制方法以及谁负责决定疼痛鸡尾酒配方。文中讨论了围绕使用可卡因作为成分的争议，并描述了配方标注日期方面的问题。我们鼓励药品与治疗委员会查阅有关疼痛鸡尾酒配方的文献，并在各自机构内重新评估疼痛鸡尾酒的使用情况。
