Cesk Patol. 1976 Nov;12(4):161-5.
Prolonged per os administration of silver nitrate solution in rats will result in the development of experimental argyrosis with particles of silver in the kidneys being deposited mainly in the glomerular basal membranes. Apart from that, particles of silver in the glomeruli were also found in the mesangioma and, in minor quantities, in podocytes and endothelial cells. Outside the glomerular structures, silver was found deposited in tubular basal membranes, in the proximal tubule epithelium and minute vessel wals. -- A discussion is presented of the possible mechanisms involved in the development of such deposits, as well as of the relationship between intravital silver depositing and some of the tissues affinity to silver, a property taken advantage of in histological methods.
在大鼠中长期经口给予硝酸银溶液会导致实验性银质沉着病的发生，肾脏中的银颗粒主要沉积在肾小球基底膜。除此之外，在肾小球系膜中也发现了银颗粒，少量存在于足细胞和内皮细胞中。在肾小球结构之外，银沉积在肾小管基底膜、近端肾小管上皮和微小血管壁中。——本文讨论了这些沉积物形成的可能机制，以及活体银沉积与某些组织对银的亲和力之间的关系，这种亲和力在组织学方法中得到了利用。
