Morrison A W, Gibson W P, Beagley H A
Clin Otolaryngol Allied Sci. 1976;1(2):153-67. doi: 10.1111/j.1365-2273.1976.tb00868.x.
Transtympanic electrocochleography has been used as a diagnostic procedure in over 250 adult patients with sensorineural deafness. No complications have been encountered. Among these patients vestibulocochlear Schwannoma (acoustic neuroma) has been confirmed in 56 ears while 11 other ears have been found to be affected by other space-occupying lesions. As a result of our observations in these patients, we would like to propose that there are at least three separate criteria to be considered in reaching or strongly suspecting a diagnosis of such pathology. These are broadening of the action potential (loss of P1), observation of a clear microphonic response, and preservation of the action potential even when using stimulus intensities which are not audible in the patients' affected ears. The merits of each of these criteria are discussed and compared with other clinical and operative findings. With the electrocochleographic techniques now employed in searching for acoustic neuromas, false negative results are rare though false positive results are still obtained.
经鼓膜电耳蜗描记术已被用作250多名感音神经性耳聋成年患者的诊断方法。未出现并发症。在这些患者中,56耳确诊为前庭蜗神经鞘瘤(听神经瘤),另有11耳发现受其他占位性病变影响。基于我们对这些患者的观察,我们建议在做出或强烈怀疑此类病变的诊断时,至少有三个独立的标准需要考虑。这些标准包括动作电位增宽(P1波消失)、清晰的微音器反应观察以及即使使用患者患耳听不见的刺激强度时动作电位仍得以保留。对每个标准的优点进行了讨论,并与其他临床和手术结果进行了比较。使用目前用于寻找听神经瘤的电耳蜗描记技术,假阴性结果很少见,不过假阳性结果仍然会出现。