[疣状表皮发育不良恶变所致鳞状细胞癌]
[Squamous cell carcinoma developing from epidermodysplasia verruciformis].
作者信息
Gross C, Basten D, Langner C
机构信息
Institut für Pathologie, Städtischen Kliniken, Kassel, Akademisches Lehrkrankenhaus der Phillips-Universität Marburg.
出版信息
Pathologe. 1999 Mar;20(2):120-4. doi: 10.1007/s002920050330.
We report on a 50-year-old man who presented with squamous cell carcinoma of the forehead skin developing from epidermodysplasia verruciformis (EV). EV is an uncommon disease characterized by flat warts or scaling macules resembling pityriasis vericolor on sun-exposed skin. Histogenetic predisposition and human papilloma virus infection play a part. As shown in our case there is, depending on HPV subtype and additional exposure to ultraviolet light, a high risk of malignant transformation. These patients require close monitoring.
我们报告了一名50岁男性，其前额皮肤鳞状细胞癌由疣状表皮发育异常（EV）发展而来。EV是一种罕见疾病，其特征为在暴露于阳光的皮肤上出现扁平疣或类似花斑癣的鳞屑性斑疹。组织发生易感性和人乳头瘤病毒感染起一定作用。如我们的病例所示，根据人乳头瘤病毒亚型以及额外的紫外线暴露情况，存在很高的恶变风险。这些患者需要密切监测。
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