Cenni B, Picard D
Département de Biologie Cellulaire, Université de Geneve, Sciences III, 30 Quai Ernest-Ansermet, 1211 Geneveve 4, Switzerland.
Trends Endocrinol Metab. 1999 Mar;10(2):41-46. doi: 10.1016/s1043-2760(98)00121-0.
Steroid receptors are known as ligand-regulated transcription factors, but more and more evidence indicates that several steroid receptors can be activated in the absence of cognate hormone by agents that fall into three separate groups: peptide growth factors, the neurotransmitter dopamine and other agents that activate cAMP-dependent protein kinase A, and the cyclins A and D1.
类固醇受体被认为是配体调节的转录因子,但越来越多的证据表明,几种类固醇受体在没有同源激素的情况下可被分为三组的物质激活:肽生长因子、神经递质多巴胺以及其他激活环磷酸腺苷(cAMP)依赖性蛋白激酶A的物质,还有细胞周期蛋白A和D1。