益肾泄浊方对慢性肾衰竭大鼠系膜细胞的影响
[Effect of yishen xiezhou recipe on mesangium cell of chronic renal failure rats].
作者信息
Xu C G, Wu Z Y
机构信息
Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine.
出版信息
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Jul;17(7):423-4.
PMID:10322865
Abstract
OBJECTIVE
To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation.
METHODS
YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed.
RESULTS
The serum could obviously inhibit the MSC proliferation. Compared with control rats to which physiological saline was given, the difference was significant (P < 0.01).
CONCLUSION
YSXZR could postpone CRF progress.
摘要
目的
观察益肾泄浊方对肾小球系膜细胞（MSC）增殖的影响。
方法
对健康大鼠和实验性慢性肾衰竭（CRF）大鼠进行益肾泄浊方灌胃，观察含药血清对MSC增殖的影响。
结果
该血清能明显抑制MSC增殖。与给予生理盐水的对照大鼠相比，差异有统计学意义（P<0.01）。
结论
益肾泄浊方能延缓慢性肾衰竭的进展。
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