Xie Y M, Zhang F Z, Zhou W Q
Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Sep;17(9):526-30.
To assess the effect of Bugu Shengsui capsule (BGSSC) in treating primary osteoporosis.
Using double energy X-ray bone densimeter and radioimmunoassay (RIA), the effect of BGSSC in treating primary osteoporosis (OP) with Kidney-Yang Deficiency syndrome.
The clinical markedly effective and total effective rates of BGSSC were 46% and 82%, respectively. The rate of TCM group is significantly higher than that of the control group (Vitamin D plus calcium). BGSSC could improve bone mineral density by the verification of double energy X-ray bone dansity (DEXA). It could also increase the level of serum calcitonin, luteinizing hormone and calcium, decrease the activity of parathyroid hormone.
The effects of BGSSC on primary OP included increasing patient's bone mineral density, depressing bone resorption and decreasing bone loss.
评估补骨生髓胶囊（BGSSC）治疗原发性骨质疏松症的效果。
采用双能X线骨密度仪和放射免疫分析法（RIA），观察BGSSC治疗肾阳虚型原发性骨质疏松症（OP）的效果。
BGSSC的临床显效率和总有效率分别为46%和82%。中药组的有效率显著高于对照组（维生素D加钙剂）。通过双能X线骨密度仪（DEXA）验证，BGSSC可提高骨密度。它还能提高血清降钙素、黄体生成素和钙的水平，降低甲状旁腺激素的活性。
BGSSC对原发性OP的作用包括提高患者骨密度、抑制骨吸收和减少骨质流失。
