Liu L Y, Sun Z Q, Xiang H
Hunan Academy of TCM, Changsha.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Oct;17(10):616-9.
To study the mechanism of delaying senility by using the principle of replenishing Qi and promoting blood circulation(RQPBC).
The following determinations were carried out in the natural-senile animals which have Qi deficiency and blood stasis Syndrome(24 month old rat) after the treatment. Hemorheological indexes, brain noradrenaline (NE), adrenocorticotropine(ACTH), beta endorphin, cortisol, estradiol, testosterone, interleukin-II (IL-2), tumour necrosis factor (TNF) in the blood, and rat spleen's lymphocyte transformation and induction of IL-2 and the activity of natural killer cells (NKC).
The senile rat's above indexes decreased obviously (control: young rats), and by using this principle, all indexes were improved respectively. But these indexes in the young rats cannot be changed by applying this principle.
The results indicated that this principle could improve senile body's regulation of neuro-immuno endocrinologic network and keep homeostasis.
运用益气活血原理研究延缓衰老的机制。
对具有气虚血瘀证的自然衰老动物（24月龄大鼠）治疗后进行以下测定。血液流变学指标、脑中去甲肾上腺素（NE）、促肾上腺皮质激素（ACTH）、β-内啡肽、皮质醇、雌二醇、睾酮、白细胞介素-II（IL-2）、肿瘤坏死因子（TNF），以及大鼠脾脏淋巴细胞转化、IL-2诱导和自然杀伤细胞（NKC）活性。
老年大鼠上述指标明显降低（对照组：年轻大鼠），运用该原理后各项指标分别得到改善。但年轻大鼠运用该原理后这些指标无变化。
结果表明该原理可改善老年机体神经-免疫-内分泌网络的调节并维持内环境稳定。
