[Immunohistochemical distribution of atrial natriuretic peptides in the external wall of cochlear duct of guinea pigs].

The paper presents the distribution of the atrial natriuretic peptides (ANP) in the external wall of each turn of the cochlear duct of guinea pigs by an immunohistochemical technique (ABC method). ANP immunoreactivity (ANP-IR) was found in the strial vasculayis, sprial prominence, cells of external suicus and sprial ligament of the external wall of the vestibular canal and media canal. But no positive immunoreactive products were found in the spiral ligament of the external wall of scala tympanity. The results suggest that ANP of the external wall of the cochlear duct may play an important role in the formation of endolymphe. ANP-IR was difference in spiral ligament of in these scala. But their physiological function was different.