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脊髓硬脊膜动静脉瘘治疗患者的长期随访及预后

Long-term follow-up and outcome in patients treated for spinal dural arteriovenous fistula.

作者信息

Behrens S, Thron A

机构信息

Department of Neurology, University Hospital Mannheim, University of Heidelberg, Klinikum Mannheim, Mannheim, Germany.

出版信息

J Neurol. 1999 Mar;246(3):181-5. doi: 10.1007/s004150050331.

Abstract

Clinical outcome was examined in 21 patients treated for spinal dural arteriovenous fistula after 5-50 months. We compared the neurological condition (motor function, pain, sensory disturbance, vegetative dysfunction) and Barthel index before and after fistula occlusion. Neurological impairment was assessed as improved, unchanged, or deteriorated. All patients initially showed paraparesis of varying degree, and a sensory loss with a defined level in 81% before treatment. The greatest postoperative change that we measured was in motor activity (67% improved), and the most important deterioration was in male potency (28% deteriorated). We observed unchanged or absent symptoms in pain in 71% of our patients. We were thus able not only to stop but even to reverse the progression of symptoms and the degree of disability. On average, neurological symptoms stabilized within 1 year. The results of this study confirm that spinal dural arteriovenous fistula should be treated as early as possible after diagnosis.

摘要

对21例接受脊髓硬脊膜动静脉瘘治疗的患者在术后5 - 50个月进行了临床结果检查。我们比较了瘘管闭塞前后的神经状况(运动功能、疼痛、感觉障碍、自主神经功能障碍)和巴氏指数。神经功能损害评估为改善、不变或恶化。所有患者最初均表现出不同程度的双下肢轻瘫,治疗前81%的患者有明确节段性感觉丧失。我们测得术后最大的变化是运动活动(67%改善),最重要的恶化是男性性功能(28%恶化)。我们观察到71%的患者疼痛症状未改变或消失。因此,我们不仅能够阻止症状进展,甚至还能逆转症状进展和残疾程度。平均而言,神经症状在1年内稳定下来。本研究结果证实,脊髓硬脊膜动静脉瘘在诊断后应尽早治疗。

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