Pulimood A B, Ramakrishna B S, Mathan M M
Wellcome Trust Research Laboratory, Christian Medical College and Hospital, Vellore 632004, India.
Gut. 1999 Jun;44(6):881-5. doi: 10.1136/gut.44.6.881.
The case is reported of a young adult man with collagenous gastritis, an extremely rare disorder with only three case reports in the English literature, who subsequently presented with collagenous colitis. Sequential gastric biopsies showed a notable increase in thickness of the subepithelial collagen band. Ultrastructural study of gastric and rectal mucosa showed the characteristic subepithelial band composed of haphazardly arranged collagen fibres, prominent degranulating eosinophils, and activated pericryptal fibroblasts.
报告了一例患有胶原性胃炎的年轻成年男性病例,胶原性胃炎是一种极为罕见的疾病,英文文献中仅有三例病例报告,该患者随后又出现了胶原性结肠炎。连续的胃活检显示上皮下胶原带厚度显著增加。胃和直肠黏膜的超微结构研究显示,特征性的上皮下带由杂乱排列的胶原纤维、突出的脱颗粒嗜酸性粒细胞和活化的隐窝周围成纤维细胞组成。