Perner A, Bugge K, Lyng K M, Schulze S, Kristensen P A, Bendtsen A
Department of Anaesthesia, Sundby Hospital, University of Copenhagen, Denmark.
Br J Anaesth. 1999 Jan;82(1):137-9. doi: 10.1093/bja/82.1.137.
Hyperkalaemia with ECG changes had been noted during prolonged carbon dioxide pneumoperitoneum in pigs. We have compared plasma potassium concentrations during surgery in 11 patients allocated randomly to undergo either laparoscopic or open appendectomy and in another 17 patients allocated randomly to either carbon dioxide pneumoperitoneum or abdominal wall lifting for laparoscopic colectomy. Despite an increasing metabolic acidosis, prolonged carbon dioxide pneumoperitoneum resulted in only a slight increase in plasma potassium concentrations, which was both statistically and clinically insignificant. Thus hyperkalaemia is unlikely to develop in patients with normal renal function undergoing carbon dioxide pneumoperitoneum for laparoscopic surgery.
在猪长时间二氧化碳气腹过程中已观察到伴有心电图改变的高钾血症。我们比较了11例随机分配接受腹腔镜或开腹阑尾切除术的患者以及另外17例随机分配接受二氧化碳气腹或腹壁提拉法进行腹腔镜结肠切除术的患者手术期间的血浆钾浓度。尽管代谢性酸中毒不断加重，但长时间二氧化碳气腹仅导致血浆钾浓度略有升高，在统计学和临床上均无显著意义。因此，对于肾功能正常的患者，在接受二氧化碳气腹进行腹腔镜手术时不太可能发生高钾血症。
