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雄激素对大鼠胎儿尿道球腺和巴氏腺分化的影响(作者译)

[The effect of androgens upon the differentiation of Cowper and Bartholin glands in rat fetuses (author's transl)].

作者信息

Vilanova Trias J, San Molina J

出版信息

Reproduccion. 1976 Jul-Dec;3(3-4):265-72.

PMID:1032597
Abstract

In the present paper, a study is made of the normal structure shown in Bartholin and Cowper glands of 100 female fetuses and 100 male fetuses of Wistar rats at the end of gestation, with the structure of bulbouretral glands that formed in 70 female fetuses of the same species and period of gestation masculinized by androgens. In relation to the Bartholin glands, whose bilateral sketch is constant in the fetuses, we can affirm that it shows significant differences of structure with regards to the sketch of the Cowper gland. On the opposite, the histologycal details of the latter, are entirely identical to those shown by the bulbouretral glands of the masculinized female fetuses, a fact which permits us to affirm that these are authentic Cowper glands, not only because of their position, but also because of their structure. This morphological data corresponds to a masculinization phenomenon and demonstrates that the Bartholin and Cowper glands are very sensitive to the effect of androgens during gestation.

摘要

在本论文中,对妊娠末期100只雌性Wistar大鼠胎儿和100只雄性Wistar大鼠胎儿的巴氏腺和尿道球腺的正常结构进行了研究,同时研究了同一物种、相同妊娠期的70只雌性胎儿所形成的尿道球腺的结构,这些雌性胎儿的尿道球腺因雄激素作用而男性化。关于巴氏腺,其双侧形态在胎儿中是恒定的,我们可以确定,与尿道球腺的形态相比,巴氏腺显示出显著的结构差异。相反,后者的组织学细节与男性化雌性胎儿的尿道球腺所显示的完全相同,这一事实使我们能够确定这些是真正的尿道球腺,不仅因为它们的位置,还因为它们的结构。这一形态学数据对应于一种男性化现象,表明巴氏腺和尿道球腺在妊娠期对雄激素的作用非常敏感。

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Reproduccion. 1976 Jul-Dec;3(3-4):265-72.
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