Manjunath B V, Mullasari S A, Jaiswal P K, Faizal A, Agarwal R, Cherian K M, Srividhya K
Institute of Cardiovascular Diseases, Madras Medical Mission, Chennai.
Indian Heart J. 1999 Jan-Feb;51(1):55-8.
Transmyocardial laser revascularisation has emerged as a new therapeutic option for patients with severe diffuse coronary artery disease refractory to conventional modes of therapy. One hundred and two patients underwent isolated transmyocardial laser revascularisation between December 1994 and November 1997. After transmyocardial laser revascularisation, angina class improved from 2.56 +/- 0.8 to 0.8 +/- 0.9 by the end of one year and 54 percent patients were angina-free. Treadmill test workload increased from 3.6 +/- 1.7 METS pre-operatively to 6.0 +/- 3.4 METS (p < 0.005) at the end of one year's follow-up. However, left ventricle ejection fraction by MUGA slightly decreased (p = NS) at the end of one year. We conclude that transmyocardial laser revascularisation provides symptomatic benefit, improves quality of life and objectively improves the exercise tolerance at 12 months post-procedure.
对于传统治疗方式难以奏效的严重弥漫性冠状动脉疾病患者，心肌激光血运重建术已成为一种新的治疗选择。1994年12月至1997年11月期间，102例患者接受了单纯心肌激光血运重建术。心肌激光血运重建术后，到一年结束时，心绞痛分级从2.56±0.8改善至0.8±0.9，54%的患者心绞痛症状消失。在一年随访结束时，平板运动试验负荷从术前的3.6±1.7代谢当量增加至6.0±3.4代谢当量（p<0.005）。然而，一年结束时，门电路心血池显像测定的左心室射血分数略有下降（p=无统计学意义）。我们得出结论，心肌激光血运重建术能带来症状改善，提高生活质量，并在术后12个月客观上改善运动耐量。
