Kan C C, Breteler M H, van der Ven A H, Zitman F G
Department of Psychiatry, University of Nijmegen Research Group on Addictive Behaviours (UNRAB), University of Nijmegen, University Hospital, The Netherlands.
Addiction. 1998 Mar;93(3):349-59. doi: 10.1046/j.1360-0443.1998.9333494.x.
To evaluate the homogeneity of the elements of the Substance Dependence Syndrome (SDS) as applied to benzodiazepines (BZDs) by Rasch modelling.
The Rasch scaling model was applied to data obtained by administering the SCAN (Schedules for Clinical Assessments in Neuropsychiatry) substance dependence sections. Subsequently, Rasch-homogeneous sets of DSM-III-R and ICD-10 BZD dependence criteria were assessed for subject and item discriminability. To support their construct validity a theoretical rationale was formulated based on the Rasch scale values.
A heterogeneous sample of 599 outpatient BZD users.
Only particular subsets of the DSM-III-R and ICD-10 BZD dependence criteria met the requirements for Rasch-homogeneity, which appears to be due to medical aspects of BZD use. The subject and item discriminability results were sufficiently good.
The DSM-III-R and ICD-10 BZD dependence constructs may need to be redefined. The use of a BZD dependence severity model based on a Rasch-homogeneous scale appears to have greater clinical value than a dichotomous diagnostic model based on an arbitrary cut-off point. We recommend Rasch modelling to investigate the homogeneity of the elements of the SDS across other psychoactive substances.
通过拉施模型评估应用于苯二氮䓬类药物(BZD)的物质依赖综合征(SDS)各要素的同质性。
将拉施量表模型应用于通过实施神经精神病学临床评估时间表(SCAN)物质依赖部分所获得的数据。随后,对DSM-III-R和ICD-10苯二氮䓬类药物依赖标准的拉施同质集进行了受试者和项目区分度评估。为支持其结构效度,基于拉施量表值制定了理论依据。
599名门诊苯二氮䓬类药物使用者的异质性样本。
只有DSM-III-R和ICD-10苯二氮䓬类药物依赖标准的特定子集符合拉施同质性要求,这似乎是由于苯二氮䓬类药物使用的医学方面原因。受试者和项目区分度结果足够好。
DSM-III-R和ICD-10苯二氮䓬类药物依赖结构可能需要重新定义。基于拉施同质量表的苯二氮䓬类药物依赖严重程度模型的应用似乎比基于任意临界点的二分诊断模型具有更大的临床价值。我们建议使用拉施模型来研究跨其他精神活性物质的SDS各要素的同质性。