• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Human mitochondrial complex I in health and disease.

作者信息

Smeitink J, van den Heuvel L

机构信息

Department of Pediatrics, Nijmegen Center for Mitochondrial Disorders, University Hospital Nijmegen, Nijmegen, The Netherlands.

出版信息

Am J Hum Genet. 1999 Jun;64(6):1505-10. doi: 10.1086/302432.

DOI:10.1086/302432
PMID:10330338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1377894/
Abstract
摘要

相似文献

1
Human mitochondrial complex I in health and disease.健康与疾病状态下的人类线粒体复合体I
Am J Hum Genet. 1999 Jun;64(6):1505-10. doi: 10.1086/302432.
2
Escherichia coli NADH dehydrogenase I, a minimal form of the mitochondrial complex I.大肠杆菌NADH脱氢酶I，线粒体复合物I的一种最小形式。
Biochem Soc Trans. 1993 Nov;21(4):998-1001. doi: 10.1042/bst0210998.
3
The nuclear-encoded human NADH:ubiquinone oxidoreductase NDUFA8 subunit: cDNA cloning, chromosomal localization, tissue distribution, and mutation detection in complex-I-deficient patients.核编码的人类NADH：泛醌氧化还原酶亚基NDUFA8：cDNA克隆、染色体定位、组织分布以及在复合物I缺陷患者中的突变检测
Hum Genet. 1998 Nov;103(5):557-63. doi: 10.1007/s004390050869.
4
Human mitochondrial complex I dysfunction.人类线粒体复合体I功能障碍。
Biochim Biophys Acta. 1992 Jul 17;1101(2):198-203. doi: 10.1016/s0005-2728(05)80019-2.
5
Higher plant mitochondria encode an homologue of the nuclear-encoded 30-kDa subunit of bovine mitochondrial complex I.高等植物线粒体编码牛线粒体复合体I的核编码30 kDa亚基的同源物。
Eur J Biochem. 1993 Nov 1;217(3):831-8. doi: 10.1111/j.1432-1033.1993.tb18311.x.
6
Identification of two genes of Rhodobacter capsulatus coding for proteins homologous to the ND1 and 23 kDa subunits of the mitochondrial Complex I.鉴定出荚膜红细菌的两个基因，它们编码的蛋白质与线粒体复合体I的ND1和23 kDa亚基同源。
FEBS Lett. 1992 Apr 20;301(2):215-8. doi: 10.1016/0014-5793(92)81250-p.
7
cDNA sequence and chromosomal localization of the NDUFS8 human gene coding for the 23 kDa subunit of the mitochondrial complex I.编码线粒体复合体I 23 kDa亚基的人类基因NDUFS8的cDNA序列及染色体定位
Biochim Biophys Acta. 1997 Mar 20;1351(1-2):37-41. doi: 10.1016/s0167-4781(97)00020-1.
8
Molecular characterisation of the 76 kDa iron-sulphur protein subunit of potato mitochondrial complex I.马铃薯线粒体复合体I的76 kDa铁硫蛋白亚基的分子特征分析
Plant Cell Physiol. 1998 Apr;39(4):373-81. doi: 10.1093/oxfordjournals.pcp.a029380.
9
The proton-pumping respiratory complex I of bacteria and mitochondria and its homologue in chloroplasts.细菌和线粒体的质子泵呼吸复合体I及其在叶绿体中的同源物。
FEBS Lett. 1995 Jun 26;367(2):107-11. doi: 10.1016/0014-5793(95)00548-n.
10
Cloning of ndhK from soybean chloroplasts using antibodies raised to mitochondrial complex I.利用针对线粒体复合体I产生的抗体从大豆叶绿体中克隆ndhK
Plant Mol Biol. 1992 Dec;20(5):887-95. doi: 10.1007/BF00027160.

引用本文的文献

1
Blockage of NDUFB9-SCD1 pathway inhibits adipogenesis : Blockage of NDUFB9-SCD1 pathway inhibits adipogenesis.阻断 NDUFB9-SCD1 通路抑制脂肪生成：阻断 NDUFB9-SCD1 通路抑制脂肪生成。
J Physiol Biochem. 2022 May;78(2):377-388. doi: 10.1007/s13105-022-00876-7. Epub 2022 Feb 5.
2
An Overview of Mitochondrial Protein Defects in Neuromuscular Diseases.神经肌肉疾病中线粒体蛋白缺陷概述。
Biomolecules. 2021 Nov 4;11(11):1633. doi: 10.3390/biom11111633.
3
Tackling Dysfunction of Mitochondrial Bioenergetics in the Brain.解决大脑中线粒体生物能量功能障碍
Int J Mol Sci. 2021 Aug 3;22(15):8325. doi: 10.3390/ijms22158325.
4
Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions.线粒体结构与在正常和疾病条件下的生物能量学。
Int J Mol Sci. 2021 Jan 8;22(2):586. doi: 10.3390/ijms22020586.
5
Comparison of regulatory networks of E74-like factor 1 and cold-shock domain-containing E1 in breast cancer cell lines using ChIP datasets.利用染色质免疫沉淀数据集比较乳腺癌细胞系中E74样因子1和含冷休克结构域E1的调控网络
Exp Ther Med. 2020 Dec;20(6):245. doi: 10.3892/etm.2020.9375. Epub 2020 Oct 22.
6
Transcriptome analysis reveals a molecular understanding of nicotinamide and butyrate sodium on meat quality of broilers under high stocking density.转录组分析揭示了高饲养密度下烟酰胺和丁酸钠对肉鸡肉质的分子机制。
BMC Genomics. 2020 Jun 18;21(1):412. doi: 10.1186/s12864-020-06827-0.
7
Madecassic Acid Derivatives as Potential Anticancer Agents: Synthesis and Cytotoxic Evaluation.玛卡烯酸衍生物作为潜在的抗癌剂：合成与细胞毒性评价。
J Nat Prod. 2019 Aug 23;82(8):2094-2105. doi: 10.1021/acs.jnatprod.8b00864. Epub 2019 Jul 25.
8
Movement disorders in mitochondrial disease.线粒体病中的运动障碍。
J Neurol. 2018 May;265(5):1230-1240. doi: 10.1007/s00415-017-8722-6. Epub 2018 Jan 6.
9
Genome-wide hepatic DNA methylation changes in high-fat diet-induced obese mice.高脂饮食诱导的肥胖小鼠肝脏全基因组DNA甲基化变化
Nutr Res Pract. 2017 Apr;11(2):105-113. doi: 10.4162/nrp.2017.11.2.105. Epub 2017 Mar 15.
10
Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells.核黄素缺乏诱导 HepG2 细胞蛋白质组图谱发生显著变化。
Sci Rep. 2017 Apr 3;7:45861. doi: 10.1038/srep45861.

本文引用的文献

1
Subacute necrotizing encephalomyelopathy in an infant.一名婴儿的亚急性坏死性脑脊髓病
J Neurol Neurosurg Psychiatry. 1951 Aug;14(3):216-21. doi: 10.1136/jnnp.14.3.216.
2
Mutant NDUFV1 subunit of mitochondrial complex I causes leukodystrophy and myoclonic epilepsy.线粒体复合物I的突变型NDUFV1亚基导致脑白质营养不良和肌阵挛性癫痫。
Nat Genet. 1999 Mar;21(3):260-1. doi: 10.1038/6772.
3
Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q13.人类 NDUFB9 基因：基因组结构及一个可能与耳聋疾病相关的候选基因定位于 8q13 染色体。
Hum Hered. 1999 Mar;49(2):75-80. doi: 10.1159/000022848.
4
cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.烟酰胺腺嘌呤二核苷酸（NADH）：泛醌氧化还原酶八个核编码亚基的互补脱氧核糖核酸（cDNA）：人类复合体I的cDNA特性分析已完成。
Biochem Biophys Res Commun. 1998 Dec 18;253(2):415-22. doi: 10.1006/bbrc.1998.9786.
5
SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome.编码参与细胞色素c氧化酶生物合成的一种因子的SURF1，在Leigh综合征中发生突变。
Nat Genet. 1998 Dec;20(4):337-43. doi: 10.1038/3804.
6
Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency.与细胞色素c氧化酶缺乏相关的Leigh病中SURF-1的突变。
Am J Hum Genet. 1998 Dec;63(6):1609-21. doi: 10.1086/302150.
7
The first nuclear-encoded complex I mutation in a patient with Leigh syndrome.一名患有 Leigh 综合征的患者出现首例核编码的复合体 I 突变。
Am J Hum Genet. 1998 Dec;63(6):1598-608. doi: 10.1086/302154.
8
NADH:ubiquinone oxidoreductase from bovine heart mitochondria: sequence of a novel 17.2-kDa subunit.牛心线粒体的NADH：泛醌氧化还原酶：一种新型17.2 kDa亚基的序列
FEBS Lett. 1998 Nov 6;438(3):301-5. doi: 10.1016/s0014-5793(98)01317-9.
9
Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex.线粒体外膜前体蛋白转位酶：一般导入孔复合体的分子剖析与组装
Mol Cell Biol. 1998 Nov;18(11):6515-24. doi: 10.1128/MCB.18.11.6515.
10
Tom40 forms the hydrophilic channel of the mitochondrial import pore for preproteins [see comment].Tom40形成用于前体蛋白的线粒体输入孔的亲水性通道[见评论]。
Nature. 1998 Oct 1;395(6701):516-21. doi: 10.1038/26780.