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血管炎中的胃肠道和肾脏受累:过敏性紫癜的管理策略

Gastrointestinal and renal involvement in vasculitis: management strategies in Henoch-Schönlein purpura.

作者信息

Szer I S

机构信息

University of California-San Diego School of Medicine, USA.

出版信息

Cleve Clin J Med. 1999 May;66(5):312-7. doi: 10.3949/ccjm.66.5.312.

Abstract

The joint pain, inflammation, and painful cutaneous edema of Henoch-Schölein purpura (HSP) are effectively treated with analgesics, nonsteroidal anti-inflammatory agents, and corticosteroids, but the optimal management of HSP-associated gastrointestinal and renal involvement has not yet been determined. The results of mostly anecdotal and uncontrolled studies favor a short course of oral corticosteroids for severe abdominal pain and aggressive immunosuppressive therapy for patients with progressive HSP nephritis.

摘要

亨诺-许兰紫癜(HSP)的关节疼痛、炎症及疼痛性皮肤水肿可通过镇痛药、非甾体抗炎药和皮质类固醇有效治疗,但HSP相关胃肠道和肾脏受累的最佳管理方案尚未确定。大多为轶事性和非对照研究的结果支持对严重腹痛采用短期口服皮质类固醇治疗,对进行性HSP肾炎患者采用积极的免疫抑制治疗。

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