Matsuda Y, Nakanishi Y, Mizuno Y
Racehorse Clinic, Japan Racing Association Miho Training Center, Ibaraki-ken, Japan.
J Vet Med Sci. 1999 Mar;61(3):221-5. doi: 10.1292/jvms.61.221.
Occlusion of the internal carotid artery by insertion of intravascular platinum microcoils for guttural pouch mycosis was experimentally evaluated in 9 healthy adult Thoroughbred horses. The internal carotid artery was ligated to its origin, and an arteriotomy was made distal to the ligature, which was then occluded by insertion of the microcoil approximately 13 cm distal to its origin. Cessation of blood flow was determined visually and by angiography at the arteriotomy site. Six horses were evaluated for complication clinically and by endoscopy after surgery. One horse was necropsied after 30 days of surgery for histological evaluation of artery thrombus formation. In the other 3 horses, the blood flow of the right internal carotid artery was monitored, before and after microcoil occlusion of the left internal carotid artery. One or 2 microcoils stopped blood flow within a few minutes. No other abnormal findings were observed clinically. Thrombus was observed in the occluded segment of 1 horse 30 days after insertion; but no abnormalities were detected. The blood flow in the right internal carotid artery increased by approximately 28-58% after occlusion of the left internal carotid artery. This microcoil vascular occlusion technique causes an effective thrombosis, and based on experimental studies and clinical application in 2 horses with epistaxis due to guttural pouch mycosis, this technique would appear to be safe and efficacious.
在9匹健康成年纯种马身上对通过血管内插入铂微线圈来闭塞颈内动脉以治疗咽囊真菌病进行了实验评估。将颈内动脉在其起始处结扎，在结扎远端进行动脉切开，然后在距其起始处约13厘米处插入微线圈来闭塞动脉。通过肉眼观察和动脉切开部位的血管造影来确定血流是否停止。6匹马在术后进行了临床评估和内镜检查。1匹马在手术后30天进行尸检以对动脉血栓形成进行组织学评估。在另外3匹马中，在左颈内动脉微线圈闭塞前后监测右颈内动脉的血流。1个或2个微线圈在几分钟内就使血流停止。临床上未观察到其他异常发现。在插入微线圈30天后，在1匹马的闭塞段观察到血栓形成，但未检测到异常情况。左颈内动脉闭塞后，右颈内动脉的血流增加了约28% - 58%。这种微线圈血管闭塞技术能有效形成血栓，并且基于对2匹因咽囊真菌病鼻出血的马的实验研究和临床应用，该技术似乎是安全有效的。
