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患有糖尿病的少数族裔青少年出现代谢控制问题的风险。

Risk for metabolic control problems in minority youth with diabetes.

作者信息

Delamater A M, Shaw K H, Applegate E B, Pratt I A, Eidson M, Lancelotta G X, Gonzalez-Mendoza L, Richton S

机构信息

University of Miami School of Medicine, FL 33101, USA.

出版信息

Diabetes Care. 1999 May;22(5):700-5. doi: 10.2337/diacare.22.5.700.

Abstract

OBJECTIVE

We examined and quantified the degree of risk for poor glycemic control and hospitalizations for diabetic ketoacidosis (DKA) among black, Hispanic, and white children and adolescents with diabetes.

RESEARCH DESIGN AND METHODS

We examined ethnic differences in metabolic control among 68 black, 145 Hispanic, and 44 white children and adolescents with type 1 diabetes (mean age 12.9 [range 1-21] years), who were primarily of low socioeconomic status. Clinical and demographic data were obtained by medical chart review. Glycohemoglobins were standardized and compared across ethnic groups. Odds ratios among the ethnic groups for poor glycemic control and hospitalizations for DKA were also calculated.

RESULTS

The ethnic groups were not different with respect to age, BMI, insulin dose, or hospitalizations for DKA, but black children were older at the time of diagnosis than Hispanics (P < 0.05) and were less likely to have private health insurance than white and Hispanic children (P < 0.001). Black youths had higher glycohemoglobin levels than white and Hispanic youths (P < 0.001 after controlling for age at diagnosis). Black youths were also at greatest risk for poor glycemic control (OR = 3.9, relative to whites; OR = 2.5, relative to Hispanics).

CONCLUSIONS

These results underscore and quantify the increased risk for glycemic control problems of lower-income, black children with diabetes. In the absence of effective intervention, these youths are likely to be overrepresented in the health care system as a result of increased health complications related to diabetes.

摘要

目的

我们研究并量化了患有糖尿病的黑人、西班牙裔和白人儿童及青少年血糖控制不佳和糖尿病酮症酸中毒(DKA)住院治疗的风险程度。

研究设计与方法

我们研究了68名黑人、145名西班牙裔和44名白人1型糖尿病儿童及青少年(平均年龄12.9岁[范围1 - 21岁])的代谢控制种族差异,这些儿童及青少年主要来自社会经济地位较低的群体。通过查阅病历获取临床和人口统计学数据。糖化血红蛋白进行了标准化处理并在不同种族群体间进行比较。还计算了不同种族群体中血糖控制不佳和DKA住院治疗的比值比。

结果

不同种族群体在年龄、体重指数、胰岛素剂量或DKA住院治疗方面没有差异,但黑人儿童在诊断时的年龄比西班牙裔儿童大(P < 0.05),并且与白人和西班牙裔儿童相比,拥有私人医疗保险的可能性更小(P < 0.001)。黑人青少年的糖化血红蛋白水平高于白人和西班牙裔青少年(在控制诊断时的年龄后,P < 0.001)。黑人青少年血糖控制不佳的风险也最高(相对于白人,OR = 3.9;相对于西班牙裔,OR = 2.5)。

结论

这些结果强调并量化了低收入黑人糖尿病儿童血糖控制问题风险的增加。在缺乏有效干预的情况下,由于与糖尿病相关的健康并发症增加,这些青少年在医疗保健系统中的占比可能会过高。

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