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发情周期中牛外周血浆中类固醇的浓度及倍他米松治疗的影响。

Concentration of steroids in bovine peripheral plasma during the oestrous cycle and the effect of betamethasone treatment.

作者信息

Kanchev L N, Dobson H, Ward W R, Fitzpatrick R J

出版信息

J Reprod Fertil. 1976 Nov;48(2):341-5. doi: 10.1530/jrf.0.0480341.

DOI:10.1530/jrf.0.0480341
PMID:1033280
Abstract

Testosterone, oestradiol and progesterone were measured in peripheral plasma during the oestrous cycle of 6 heifers. Oestradiol and progesterone results confirmed earlier reports. Concentration of testosterone on the day of oestrus was 40+/-3 pg/ml (mean+/-S.E.M.), and two peaks were detected during the cycle, one 7 days before oestrus (1809+/-603 pg/ml) and the other (78+/- 7 pg/ml) on the day before the onset of oestrus. The concentration of progesterone declined in most cases 1 day after the maximum concentration of testosterone. Betamethasone treatment in 5 heifers extended luteal function by an average of 10 days: plasma androstenedione and oestradiol concentrations were unaltered; cortisol values were depressed for at least 16 days after treatment; testosterone concentrations were lowered by 13+/-2-4% during treatment, and except in one heifer the peak on Day -7 was abolished.

摘要

在6头小母牛的发情周期中,测定了外周血浆中的睾酮、雌二醇和孕酮。雌二醇和孕酮的结果证实了早期的报道。发情当天睾酮浓度为40±3 pg/ml(平均值±标准误),在周期中检测到两个峰值,一个在发情前7天(1809±603 pg/ml),另一个在发情开始前一天(78±7 pg/ml)。在大多数情况下,孕酮浓度在睾酮浓度达到最大值后1天下降。对5头小母牛进行倍他米松治疗,平均延长黄体功能10天:血浆雄烯二酮和雌二醇浓度未改变;治疗后皮质醇值至少降低16天;治疗期间睾酮浓度降低了13±2.4%,除一头小母牛外,第-7天的峰值消失。

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