Phillips T J
Department of Dermatology, Boston University School of Medicine, MA 02118-2394, USA.
Postgrad Med. 1999 May 1;105(5):159-61, 165-6, 173-4 passim. doi: 10.3810/pgm.1999.05.1.744.
The cause of a leg ulcer should be determined before a course of treatment is undertaken, and this often can be accomplished through history taking, physical examination, and use of simple noninvasive testing. Most leg ulcers are caused by venous disease, arterial insufficiency, neuropathy, or a combination of these factors. Complete management should address the patient's general health as well as specific findings, and treatment of any underlying cause is paramount. In venous ulcers, compression is the cornerstone of treatment, and a variety of effective stockings and other compression devices are available. Arterial ulcers usually require reestablishment of an adequate vascular supply, often through surgery. Neuropathic ulcers need thorough debridement to allow good granulation and epithelialization. Five types of occlusive dressings are available that achieve debridement less painfully but also more slowly than the surgical approach. Several adjunctive methods are now available that facilitate successful therapy in these ulcers, which have often been considered nonhealing wounds.
在开始治疗疗程之前,应确定腿部溃疡的病因,这通常可以通过病史采集、体格检查以及使用简单的非侵入性检测来完成。大多数腿部溃疡是由静脉疾病、动脉供血不足、神经病变或这些因素的组合引起的。全面的管理应关注患者的整体健康状况以及具体检查结果,治疗任何潜在病因至关重要。对于静脉性溃疡,加压是治疗的基石,有多种有效的弹力袜和其他加压装置可供使用。动脉性溃疡通常需要恢复充足的血管供应,常常需要通过手术来实现。神经性溃疡需要彻底清创,以促进良好的肉芽形成和上皮化。有五种类型的封闭敷料,它们清创时疼痛较轻,但比手术方法清创速度更慢。现在有几种辅助方法可用于促进这些通常被认为是不愈合伤口的溃疡的成功治疗。