Lanz O I, Lewis D D, Madison J B, Miller G J, Martin D E
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, USA.
Vet Surg. 1999 May-Jun;28(3):161-70. doi: 10.1053/jvet.1999.0161.
Compare the biomechanical characteristics of screw and wire fixation with and without polymethylmethacrylate (PMMA) re-enforcement for acetabular osteotomy stabilization in dogs.
Pelves removed from 8 adult mixed breed dogs weighing between 25 and 30 kg.
The pubic symphysis of each pelvis was split and a central transverse acetabular osteotomy was performed. One hemipelvis from each dog was stabilized with the composite fixation (interfragmentary Kirschner wire, two screws and a figure-of-eight orthopedic wire with PMMA). The contralateral hemipelves was stabilized with an interfragmentary Kirschner wire, two screws, and a figure-of-eight orthopedic wire without PMMA. All hemipelves were tested in bending by using a materials testing machine at a cross head speed of 5 mm/min. An extensometer was placed on the dorsomedial surface of the hemipelves centered over acetabular osteotomy to record distraction of the osteotomy during loading. A load/deformation curve and a load/distraction curve was produced for each hemipelvis. The slope for the initial linear portion of the load/deformation curve and the load/distraction curve, yield load and maximum load sustained were compared between repair groups using a paired t-test with P < .05 considered significant.
The slope of the load/deformation curve was significantly greater (P = .001) for hemipelves stabilized with the composite fixation (mean +/- SD: 69 +/- 18 N/mm) compared with hemipelves stabilized without PMMA (mean +/- SD: 39 +/- 8 N/mm). There was no significant difference (P = .593) between repair groups in the slope of the load/distraction curves as measured on the extensometer. Yield load was significantly greater (P = .0002) for hemipelves stabilized with the composite fixation (mean +/- SD: 184 +/- 25 N) compared to hemipelves stabilized without PMMA (mean +/- SD: 74 +/- 12 N). Maximum load sustained was also significantly greater (P = .013) for hemipelves stabilized with the composite fixation (mean +/- SD: 396 +/- 71 N) compared to hemipelves stabilized without PMMA (mean +/- SD: 265 +/- 94 N). Failure of hemipelves stabilized with the composite fixation occurred primarily by ventrolateral bending of the cranial and caudal pelvic segments at the osteotomy site. Failure of hemipelves stabilized without PMMA occurred by ventrolateral bending of the cranial and caudal pelvic segments at the osteotomy site with pronounced concurrent ventrolateral rotation of the cranial pelvic segment.
PMMA improves the mechanical characteristics of acetabular fracture fixation, at least in part by neutralization of rotational forces. The results of this study justify use of PMMA as a component of the composite fixation when repairing acetabular fractures.
比较在犬髋臼截骨稳定术中使用和不使用聚甲基丙烯酸甲酯(PMMA)增强的螺钉和钢丝固定的生物力学特性。
从8只体重在25至30千克之间的成年杂种犬身上取下的骨盆。
将每个骨盆的耻骨联合劈开,并进行髋臼中央横断截骨术。每只犬的一侧半骨盆采用复合固定(骨折间克氏针、两枚螺钉和带PMMA的8字形矫形钢丝)进行稳定固定。对侧半骨盆采用骨折间克氏针、两枚螺钉和不带PMMA的8字形矫形钢丝进行稳定固定。使用材料试验机以5毫米/分钟的十字头速度对所有半骨盆进行弯曲测试。在以髋臼截骨为中心的半骨盆背内侧表面放置一个引伸计,以记录加载过程中截骨的牵张情况。为每个半骨盆生成一条载荷/变形曲线和一条载荷/牵张曲线。使用配对t检验比较修复组之间载荷/变形曲线和载荷/牵张曲线初始线性部分的斜率、屈服载荷和最大持续载荷,P <.05被认为具有统计学意义。
与未使用PMMA固定的半骨盆(平均±标准差:39±8牛/毫米)相比,采用复合固定的半骨盆(平均±标准差:69±18牛/毫米)的载荷/变形曲线斜率显著更大(P =.001)。在引伸计上测量的修复组之间的载荷/牵张曲线斜率没有显著差异(P =.593)。与未使用PMMA固定的半骨盆(平均±标准差:74±12牛)相比,采用复合固定的半骨盆(平均±标准差:184±25牛)的屈服载荷显著更大(P =.0002)。与未使用PMMA固定的半骨盆(平均±标准差:265±94牛)相比,采用复合固定的半骨盆(平均±标准差:396±71牛)的最大持续载荷也显著更大(P =.013)。采用复合固定的半骨盆的失效主要发生在截骨部位的颅侧和尾侧骨盆段的腹侧弯曲。未使用PMMA固定的半骨盆的失效发生在截骨部位的颅侧和尾侧骨盆段的腹侧弯曲,同时颅侧骨盆段有明显的腹侧旋转。
PMMA改善了髋臼骨折固定的力学特性,至少部分是通过抵消旋转力实现的。本研究结果证明在修复髋臼骨折时将PMMA用作复合固定的一个组成部分是合理的。